Author

Ashish A. Kumar

University of British ColumbiaORCID 0000-0002-8018-0237Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Nalle PentinmikkoiD· 2 shared Pekka KatajistoiD· 2 shared Sharif IqbaliD· 2 shared Alessandro Ori‬‬iD· 1 shared Alexandra RitchieiD· 1 shared Anna WebbiD· 1 shared Anne JuutiiD· 1 shared Ari P. RistimakiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Nalle PentinmikkoORCID

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2 papers

Recent·Most cited

Alanine catabolism of Paneth cells maintains intestinal stem cell function during dietary restriction

Ashish A. Kumar, Sharif Iqbal, Ernesta Nestaite, Nalle Pentinmikko, Martin E. Broberg, Jack Morikka, Ville Hietakangas, Pekka Katajisto

This study shows that Paneth cells use alanine catabolism to produce lactate, which supports intestinal stem cell function during dietary restriction.

bioRxiv · Aug 28, 2025 · PreprintCell Biology

Fetal-like reversion in the regenerating intestine is regulated by mesenchymal Asporin

Sharif Iqbal, Simon Andersson, Ernesta Nesta, Nalle Pentinmikko, Ashish A. Kumar, Sawan Kumar Jha, Daniel Borshagovski, Anna Webb, Nadja Gebert, Emma W Viitala, Alexandra Ritchie, Sandra Scharaw, Emilia Kuuluvainen, Hjalte List Larsen, Tuure Saarinen, , Pekka Katajisto

The paper shows that mesenchymal Asporin mediates fetal-like reprogramming in regenerating intestinal epithelium by modulating Tgfβ signaling through CD44.

Cell stem cell · Mar 6, 2025Peer-reviewedDevelopmental Biology