Candler A. Paige

The paper compares receptor expression diversity between central and peripheral mouse neurons using single-cell RNA sequencing and finds similar diversity overall, with exceptions in GPCRs and cytokine receptors.

This study identifies sex-specific neuroendocrine mechanisms in chronic pain, showing that prolactin receptor signaling in sensory neurons contributes to hyperalgesic priming in females but not males.

The paper creates interactome maps of ligand-receptor interactions between peripheral cell types and sensory neurons in mouse and human disease states, identifying potential therapeutic targets like EGFR.

The paper compares transcriptomes of native and cultured human and mouse dorsal root ganglia, finding reduced neuronal gene expression in culture but presence of key pharmacological targets.