A Single Mutation in an Enteric Virus Alters Tropism and Sensitivity to Microbiota
Andrea K. Erickson, Danica M. Sutherland, Olivia L. Welsh, Robert W. Maples, Terence S. Dermody, Julie K. Pfeiffer
This study shows a single amino acid change in a reovirus alters its infection outcome in mice with microbiota depletion, affecting tropism and sensitivity to microbiota-driven antiviral responses.
Proceedings of the National Academy of Sciences · Apr 16, 2025Peer-reviewedMicrobiology