Author

Christoph Helmut Rudi Senges

Ruhr University BochumORCID 0000-0002-8069-8730Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Fatih Demirbas· 1 shared Huriye Deniz UzuniD· 1 shared Jennifer Stepien· 1 shared John N. AlumasaiD· 1 shared Julia Elisabeth BandowiD· 1 shared Katrin MarcusiD· 1 shared Kenneth C. KeileriD· 1 shared Kristina TschulikiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Fatih Demirbas

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1 paper

Recent·Most cited

Trans-Translation inhibitors and copper ions synergize for enhanced antibiotic activity

Melissa Vázquez‐Hernández, Huriye Deniz Uzun, Mona Otte, Lea Schipp, Christoph Helmut Rudi Senges, Sascha Heinrich, John N. Alumasa, Jennifer Stepien, Fatih Demirbas, Paolo Cignoni, Katrin Marcus, Kristina Tschulik, Ute Kraemer, Thomas Günther Pomorski, Kenneth C. Keiler, Julia Elisabeth Bandow

This paper shows that trans-translation inhibitors KKL-40 and KKL-55 synergize with copper ions to enhance antibacterial activity against B. subtilis by causing rapid translation stalling and preventing copper toxicity response.

bioRxiv · Nov 14, 2024 · PreprintMicrobiology