The role of a single non-coding nucleotide in the evolution of an epidemic African clade of Salmonella
Disa L. Hammarlöf, Carsten Kröger, Siân V. Owen, Rocı́o Canals, Lizeth Lacharme‐Lora, Nicolas Wenner, Anna E. Schager, Timothy J. Wells, Ian R. Henderson, Paul Wigley, Karsten Hokamp, Nicholas Feasey, Melita A. Gordon, Jay C. D. Hinton
The paper identifies a non-coding SNP in the pgtE promoter of Salmonella ST313 that increases PgtE expression, contributing to serum resistance and virulence in a chicken model.
Proceedings of the National Academy of Sciences · Feb 27, 2018Peer-reviewedMolecular Biology