Wild-type and single-O-antigen repeat outer-membrane vesicles induce equivalent protection against homologous and heterologous Salmonella challenge
Areej Alshayea, Siân E. Jossi, Edith Marcial‐Juárez, Marisol Pérez-Toledo, Ruby Persaud, Anna E. Schager, Daniel Nyberg Larsen, Gvantsa Gutishvili, Jamie Pillaye, Fernanda Escobar-Riquelme, Kubra Aksu-Istil, Jack Alfred Bryant, William G. C. Horsnell, Manuel Banzhaf, Jakub Zbigniew Kaczmarek, , Adam F. Cunningham
This study shows that OMVs with different O-antigen lengths induce similar protection against Salmonella infections, and boosting enhances cross-protection.
bioRxiv · Jul 3, 2024 · PreprintImmunology