Author

Melissa Y. Yan

Oregon National Primate Research CenterORCID 0000-0002-8079-7923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Brittany L. DaughtryiD· 2 shared Lucia CarboneiD· 2 shared Shawn L. ChaveziD· 2 shared Suzanne S. FeiiD· 2 shared Andrew AdeyiD· 1 shared Brett A. DavisiD· 1 shared Byung S. ParkiD· 1 shared Jimi L. RosenkrantziD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Brittany L. DaughtryORCID

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2 papers

Recent·Most cited

Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development

Kelsey E. Brooks, Brittany L. Daughtry, Brett A. Davis, Melissa Y. Yan, Suzanne S. Fei, Lucia Carbone, Shawn L. Chavez

The paper investigates molecular mechanisms of aneuploidy during early mammalian embryogenesis, revealing the role of mitotic checkpoint proteins and chromosomal mis-segregation in developmental arrest.

bioRxiv · Jul 24, 2020 · PreprintDevelopmental Biology

Single-Cell Sequencing of Primate Preimplantation Embryos Reveals Chromosome Elimination Via Cellular Fragmentation and Blastomere Exclusion

Brittany L. Daughtry, Jimi L. Rosenkrantz, Nathan H. Lazar, Suzanne S. Fei, Nash Redmayne, Kristof A. Torkenczy, Andrew Adey, Melissa Y. Yan, Lina Gao, Byung S. Park, Kimberly A. Nevonen, Lucia Carbone, Shawn L. Chavez

The paper uses single-cell DNA sequencing in non-human primates to show that chromosomal errors in embryos are encapsulated into micronuclei, fragmented, or excluded to prevent aneuploidy.

bioRxiv · May 24, 2018Developmental Biology