Shawn L. Chavez

The paper shows maternal CENP-C restores centromere symmetry in zygotes by asymmetrically recruiting to paternal centromeres, ensuring proper chromosome segregation.

This study examines ERVK11q23.3 expression in placental tissues, finding it upregulated in preterm placenta, expressed by trophoblasts, and involved in immune responses linked to preterm birth.

The paper compares transcriptomes of human and rhesus placenta, identifies differentially expressed genes, and develops novel rhesus trophoblast cell lines for studying placentation.

The paper investigates molecular mechanisms of aneuploidy during early mammalian embryogenesis, revealing the role of mitotic checkpoint proteins and chromosomal mis-segregation in developmental arrest.

The paper uses single-cell DNA sequencing in non-human primates to show that chromosomal errors in embryos are encapsulated into micronuclei, fragmented, or excluded to prevent aneuploidy.