Author

Cyrill A. Rentsch

University Hospital of BaselORCID 0000-0002-8085-6006Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Arnoud J. TempletoniD· 2 shared Clémentine Le MagneniD· 2 shared Hans‐Helge SeifertiD· 2 shared Jing WangiD· 2 shared Lukas BubendorfiD· 2 shared Raphaëlle ServantiD· 2 shared Robin DolgosiD· 2 shared Romuald ParmentieriD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Arnoud J. TempletonORCID

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2 papers

Recent·Most cited

A modular patient-derived organoid-xenograft platform reveals molecular and clinical trajectories of prostate cancer progression

Romuald Parmentier, Robin Dolgos, Raphaëlle Servant, Jing Wang, Luca Roma, Renaud Mével, Daniela Bossi, Heike Pueschel, Zoi Diamantopoulou, Tatjana Vlajnic, Frank Stenner, Arnoud J. Templeton, Hans‐Helge Seifert, Nicola Aceto, Jean-Philippe Paul. Theurillat, , Clémentine Le Magnen

This study establishes a patient-derived organoid-xenograft platform that models prostate cancer progression, identifies biomarkers, and predicts treatment response.

bioRxiv · Jan 5, 2026 · PreprintCancer Biology

ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types

Robin Dolgos, Romuald Parmentier, Jing Wang, Raphaëlle Servant, Arnoud J. Templeton, Tobias Zellweger, Alastair D. Lamb, Kirsten D. Mertz, Svetozar Subotic, Tatjana Vlajnic, Hans‐Helge Seifert, Ashkan Mortezavi, Cyrill A. Rentsch, Lukas Bubendorf, Clémentine Le Magnen

This study develops an ECM-free culture system for prostate cancer organoids, revealing diverse tumor lineages and identifying in vitro-enriched cell types through single-cell RNA sequencing.

Cell Reports · Oct 1, 2025Peer-reviewedCancer Biology