Author

Romuald Parmentier

University of BaselORCID 0000-0003-0899-8779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Clémentine Le MagneniD· 3 shared Arnoud J. TempletoniD· 2 shared Cyrill A. RentschiD· 2 shared Hans‐Helge SeifertiD· 2 shared Jing WangiD· 2 shared Lukas BubendorfiD· 2 shared Raphaëlle ServantiD· 2 shared Robin DolgosiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Clémentine Le MagnenORCID

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3 papers

Recent·Most cited

A modular patient-derived organoid-xenograft platform reveals molecular and clinical trajectories of prostate cancer progression

Romuald Parmentier, Robin Dolgos, Raphaëlle Servant, Jing Wang, Luca Roma, Renaud Mével, Daniela Bossi, Heike Pueschel, Zoi Diamantopoulou, Tatjana Vlajnic, Frank Stenner, Arnoud J. Templeton, Hans‐Helge Seifert, Nicola Aceto, Jean-Philippe Paul. Theurillat, , Clémentine Le Magnen

This study establishes a patient-derived organoid-xenograft platform that models prostate cancer progression, identifies biomarkers, and predicts treatment response.

bioRxiv · Jan 5, 2026 · PreprintCancer Biology

ECM-free patient-derived organoids preserve diverse prostate cancer lineages and uncover in vitro-enriched cell types

Robin Dolgos, Romuald Parmentier, Jing Wang, Raphaëlle Servant, Arnoud J. Templeton, Tobias Zellweger, Alastair D. Lamb, Kirsten D. Mertz, Svetozar Subotic, Tatjana Vlajnic, Hans‐Helge Seifert, Ashkan Mortezavi, Cyrill A. Rentsch, Lukas Bubendorf, Clémentine Le Magnen

This study develops an ECM-free culture system for prostate cancer organoids, revealing diverse tumor lineages and identifying in vitro-enriched cell types through single-cell RNA sequencing.

Cell Reports · Oct 1, 2025Peer-reviewedCancer Biology

IRE1 activity regulates tumour and microenvironment cell lineage states while stratifying localised and metastatic prostate cancer.

Dimitrios Doultsinos, Ingrid Tomljanović, Eleftherios D. Pilalis, Sophia M. Abusamra, Romuald Parmentier, I.E. Bridges, Sandy Figiel, Yanis Zekri, Joanna Hester, Damien A. Leach, Charlotte Lynne Bevan, Alastair D.G. Lamb, Wilbert T. Zwart, Aristotelis A. Chatziioannou, Clémentine Le Magnen, Ian Geoffrey Mills

This paper identifies IRE1 activity as a regulator of prostate cancer cell lineage states and shows its role in predicting prognosis and treatment response across localized and metastatic disease.

bioRxiv · Mar 13, 2025 · PreprintCancer Biology