PathologybioRxivPreprint
MTAP deficiency is a novel biomarker in neuroendocrine neoplasms of the lung
Magdalena M. Brune, Luca Roma, Nikolaus Deigendesch…·Lukas Bubendorf
The paper identifies MTAP deficiency as a biomarker in lung neuroendocrine neoplasms, distinguishing carcinoids from SCLC and LCNEC, and shows it is not caused by 9p21 deletion or promoter hypermethylation.
DOI 10.64898/2026.06.02.729487