Hans‐Dietmar Beer

This study activates the NLRP1 inflammasome in skin equivalents to reveal a novel signaling axis involving IL-1 and IL-36γ in psoriasis.

The paper identifies a pre-invasive malignant keratinocyte population in actinic keratosis, characterized by p63 and PITX1 regulation, and distinguishes early oncogenic programs from invasion effectors in squamous cell carcinoma.

This study shows UVA radiation causes mitochondrial DNA common deletion via ROS, while UVB causes it through a ROS-independent mechanism, identifying mtDNA CD as a biomarker for UVA-induced damage.

This study shows Malassezia promotes skin homeostasis by producing tryptophan metabolites that activate AhR, enhancing barrier function and reducing inflammation.