Author

Tugay Karakaya

University Hospital ZurichORCID 0000-0003-0683-579XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Hans‐Dietmar BeeriD· 3 shared Isabel KolmiD· 2 shared Marta SlaufovaiD· 2 shared Michela Di FilippoiD· 2 shared Mitchell Paul LevesqueiD· 2 shared Adhideb GhoshiD· 1 shared Aizhan TastanovaiD· 1 shared Alessia StaropoliiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

Hans‐Dietmar BeerORCID

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3 papers

Recent·Most cited

ImmunologyCell Death and DiseasePeer-reviewedMay 29, 2026

NLRP1 inflammasome activation in skin equivalents revealsmechanistic insights into the roles of keratinocytes in psoriasis

Michela Di Filippo, Tugay Karakaya, Marta Slaufova…·Hans‐Dietmar Beer

This study activates the NLRP1 inflammasome in skin equivalents to reveal a novel signaling axis involving IL-1 and IL-36γ in psoriasis.

1 citation

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMay 24, 2026

p63 and PITX1 sustain a pre-invasive malignant keratinocyte population in squamous cell carcinoma precursors

Ramon Staeger, Aizhan Tastanova, Adhideb Ghosh…·Reinhard Dummer

The paper identifies a pre-invasive malignant keratinocyte population in actinic keratosis, characterized by p63 and PITX1 regulation, and distinguishes early oncogenic programs from invasion effectors in squamous cell carcinoma.

DOI 10.64898/2026.05.21.725073

𝕏 PostBluesky

MicrobiologybioRxivPreprintMar 26, 2025

The skin commensal yeast Malassezia promotes tissue homeostasis via the aryl hydrocarbon receptor.

Elena Ibáñez, Michelle Stokmaier, Giuseppe Barone…·Salomé LeibundGut‐Landmann

This study shows Malassezia promotes skin homeostasis by producing tryptophan metabolites that activate AhR, enhancing barrier function and reducing inflammation.

4 citations

humanproteomics

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