This paper designs and tests a combination vaccine targeting SARS-CoV, SARS-CoV-2, and MERS using Spike proteins and adjuvants to enhance antibody responses and neutralizing capabilities.

bioRxiv · Oct 27, 2025 · PreprintImmunology

Accurate evaluation of live-virus microneutralisation for SARS-CoV-2 variant JN.1

Giulia Dowgier, Agnieszka Hobbs, David Greenwood, Marianne Shawe‐Taylor, Phoebe Stevenson-Leggett, James Bazire, Rebecca Penn, Ruth Harvey, Crick COVID serology pipeline, Legacy Investigators, Vincenzo Libri, George Kassiotis, Steve J. Gamblin, Nicola S. Lewis, Bryan Williams, Charles Swanton, , Mary Y Wu

The paper evaluates neutralising antibody titres against SARS-CoV-2 variant JN.1 using live-virus microneutralisation assays in vaccinated individuals, finding higher titres in monovalent vaccine recipients.

bioRxiv · Apr 17, 2024 · PreprintMicrobiology

Polygenic risk scores predict diabetic complications and their response to therapy

Johanne Tremblay, Mounsif Haloui, Redha Attaoua, Muhammad Ramzan Tahir, Camil Hishmih, François Harvey, François-Christophe Marois-Blanchet, Carole Long, Paul Simon, Lara Santucci, Candan Hızel, John Philip Chalmers, Michel Marre, Stephen B. Harrap, Renata Cífková, , Pavel Hamet

This paper develops a polygenic risk score model to predict diabetic complications and their response to therapy using genome-wide association study data.

Diabetologia · Jul 5, 2021Peer-reviewedGenetic & Genomic Medicine