Claire Mary Smith

This study shows bovine H5N1 influenza viruses have adapted to efficiently use NeuGc receptors in cattle, enhancing replication without significantly altering zoonotic risk.

This study identifies neutrophil myeloperoxidase (MPO) as a biomarker for RSV severity and demonstrates its utility as a functional readout for evaluating antiviral therapies in an in vitro model.

This study shows that the canine respiratory tract supports influenza A virus replication and could facilitate interspecies transmission and emergence of new IAVs.

The paper presents a donor-derived air-liquid interface model for screening antiviral combinations against RSV, with tools to assess efficacy and epithelial toxicity.

Cattle B3.13 H5N1 polymerase gained PB2 M631L and PA K497R, boosting replication in bovine and human cells via better bovine ANP32A use; later PB2 E627K and D740N add activity.

This study evaluates antiviral drug synergy and mutational signatures of RdRp inhibitors against RSV and hPIV in epithelial cell models and primary airway cultures.

This paper designs and tests a combination vaccine targeting SARS-CoV, SARS-CoV-2, and MERS using Spike proteins and adjuvants to enhance antibody responses and neutralizing capabilities.