Jose Alejandro Guevara-Patino

The paper identifies collagen remodeling as a mechanism that activates a GPCR-mediated immune checkpoint in ADGRG1+ CD8+ T cells, influencing response to immunotherapy.

This paper demonstrates that magnetoelectric nanoparticles (MENPs) can target and kill cancer cells via irreversible electroporation when activated by MRI, showing significant tumor volume reduction with no toxicities.

This paper designs and tests a combination vaccine targeting SARS-CoV, SARS-CoV-2, and MERS using Spike proteins and adjuvants to enhance antibody responses and neutralizing capabilities.

This study shows hypoxia alters T cell transcriptomes in melanoma, correlating with poor clinical outcomes in non-responders to immunotherapy.