Author

Samuel Ellis

University College LondonORCID 0000-0002-5012-4277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 4 Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:flow cytometry· 1

Frequent Co-Authors

Claire Mary SmithiD· 4 shared Amy I. Jacobs· 2 shared Christopher O’CallaghaniD· 2 shared Laura BuggiottiiD· 2 shared Mario Cortina‐BorjaiD· 2 shared Maximillian N. J. WoodalliD· 2 shared Robert E. HyndsiD· 2 shared Alejandro Arenas‐PintoiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersImmunology

Claire Mary SmithORCID

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4 papers

Recent·Most cited

Neutrophil myeloperoxidase as a functional biomarker for RSV severity: implications for in vitro therapeutic screening.

Machaela Palor, Tereza Masonou, Elisabeth J. Robinson, Wenqing Chen, Samuel Ellis, Laura Buggiotti, Amy I. Jacobs, Thomas Benoist, Paolo De Coppi, Jennifer L. Rohn, Gabriele Pollara, Mario Cortina‐Borja, Maximillian N. J. Woodall, Robert E. Hynds, Rosalind Louise Smyth, , Claire Mary Smith

This study identifies neutrophil myeloperoxidase (MPO) as a biomarker for RSV severity and demonstrates its utility as a functional readout for evaluating antiviral therapies in an in vitro model.

Nature Communications · Jul 13, 2026Peer-reviewedImmunology

Donor-derived airway ALI model for high-throughput screening of antiviral combinations with concurrent analysis of antiviral efficacy and epithelial toxicity using ciliR

Daniela Cardinale, Oriane Grant, Dani Do Hyang Lee, Samuel Ellis, Robert E. Hynds, Richard M. Angell, Christopher O’Callaghan, Mario Cortina‐Borja, Elaine Thomas, Claire Mary Smith

The paper presents a donor-derived air-liquid interface model for screening antiviral combinations against RSV, with tools to assess efficacy and epithelial toxicity.

ERJ Open Research · Feb 16, 2026Peer-reviewedMicrobiology

Antiviral drug synergy and mutational signatures in different epithelial cell models of RSV and hPIV infection

Samuel Ellis, Amy I. Jacobs, Shengyuan Zhang, Laura Buggiotti, Maximillian N. J. Woodall, Jila Ajeian, Helena J. Tutill, Charles M. Miller, Macheala Palor, Angelika Kopec, Elizabeth K. Haughey, Hongxia Ma, Mia Tomlinson, Rachel J. Williams, Christopher O’Callaghan, , Judith Breuer

This study evaluates antiviral drug synergy and mutational signatures of RdRp inhibitors against RSV and hPIV in epithelial cell models and primary airway cultures.

bioRxiv · Jan 13, 2026 · PreprintMicrobiology

Design and development of a SARS and MERS Combination Vaccine

Antonio Casal, Mohamed Deifallah Yousif, Samuel Ellis, Claire Mary Smith, Mariana O. Diniz, Bryan Williams, Paul Anthony Dalby, Gareth R. Williams, John Maxim Ward, Sudaxshina Murdan, Alejandro Arenas‐Pinto, Jose Alejandro Guevara-Patino, Delmiro Fernández-Reyes

This paper designs and tests a combination vaccine targeting SARS-CoV, SARS-CoV-2, and MERS using Spike proteins and adjuvants to enhance antibody responses and neutralizing capabilities.

bioRxiv · Oct 27, 2025 · PreprintImmunology