Jesusa Capera

The paper shows that TCR and IL2 receptor signaling synergize at the immunological synapse of CD8+ T cells, enhancing T-T synapse formation and function.

This study shows that Kv1.3 palmitoylation regulates its spatial distribution and removal from the immunological synapse, impacting T cell activation and autoimmune disease.

This paper develops a method to isolate and characterize SMAPs from NK-92 cells, showing their cytotoxic activity against tumor cells in vitro and in vivo.

This study identifies a JAK-independent mechanism of STAT3 activation in RA through TCR-dependent phosphorylation at the immunological synapse, suggesting a new therapeutic target.

This study characterizes extracellular vesicles from activated CD4 T cells and shows their pro-inflammatory effects on antigen-presenting cells, providing a resource for EV-based therapeutic development.