Author

David C. Spanswick

University of WarwickORCID 0000-0002-8129-8173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Alex ReichenbachiD· 1 shared Alexxai V. KravitziD· 1 shared Astrid C Munder· 1 shared Brian J. OldfieldiD· 1 shared Christopher V. DayasiD· 1 shared Claire J. FoldiiD· 1 shared Erika Greaves· 1 shared Felicia M. Reed· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alex ReichenbachORCID

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2 papers

Recent·Most cited

Metabolic-sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum

Alex Reichenbach, Rachel Clarke, Romana Stark, Sarah Haas Lockie, Mathieu Méquinion, Harry Dempsey, Sasha Rawlinson, Felicia M. Reed, Tara Sepehrizadeh, Michael DeVeer, Astrid C Munder, Juan Nunez-Iglesias, David C. Spanswick, Randall L. Mynatt, Alexxai V. Kravitz, , Zane Bruce Andrews

This study shows that impaired metabolic-sensing in AgRP neurons reduces dopamine release in the dorsal striatum and suppresses reward-seeking behavior, especially under hunger.

eLife · Jan 12, 2022Peer-reviewedNeuroscience

Suppression of cortico-striatal circuit activity improves cognitive flexibility and prevents body weight loss in activity-based anorexia in rats

Laura K Milton, Paul N. Mirabella, Erika Greaves, David C. Spanswick, Maarten van den Buuse, Brian J. Oldfield, Claire J. Foldi

Biological Psychiatry · Jul 2, 2020Peer-reviewedNeuroscience