NeuroscienceExperimental NeurobiologyPeer-reviewed
FAM19A5 Deficiency Mitigates the Aβ Plaque Burden and Improves Cognition in Mouse Models of Alzheimer's Disease
Sumi Park, Anu Shahapal, Sangjin Yoo…·Jae Young Seong
This study shows that reducing FAM19A5 in Alzheimer's mouse models lowers Aβ plaques and improves cognition, suggesting anti-FAM19A5 antibodies as a potential therapy.
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