Hoyun Kwak

This study shows that partial FAM19A5 deficiency in mice causes spine maturation issues, hyperactivity, and altered fear responses.

This study examines FAM19A5 expression and function in mice, finding low peripheral levels and no significant interaction with S1PR2.

This study shows that reducing FAM19A5 in Alzheimer's mouse models lowers Aβ plaques and improves cognition, suggesting anti-FAM19A5 antibodies as a potential therapy.

This paper shows that targeting FAM19A5 with a monoclonal antibody improves synaptic function and cognition in Alzheimer's disease models.