J. Simon C. Arthur

The paper investigates the role of MKK3 in adipose tissue during obesity, finding that its activation protects against insulin resistance by enhancing p38-beta signaling.

The paper identifies MSK1's role in TRPV1 upregulation in specific nociceptors, linking it to inflammatory pain and heat hyperalgesia.

This study compares IL-33-induced proteomic responses across different mast cell types and identifies p38 MAPK as a key regulator of the inflammatory programme.

This study shows that C. albicans infection suppresses BMDM immune responses to LPS or P. aeruginosa, including cytokine production, suggesting a mechanism for immune evasion.

This study shows that LPS induces metabolic changes in B cells, including amino acid uptake and cholesterol metabolism, which are essential for proliferation.

The paper shows that MSK-mediated phosphorylation of histone H3 at serine 28 couples MAPK signaling with chromatin remodelling and immediate early gene expression to induce pro-hypertrophic cardiac transcriptional responses.