Nicholas H. Elder

The paper highlights the need for a unified multimodal approach to define cellular identity in the enteric nervous system using transcriptomic and other omics data.

The paper shows that lineage origins shape gene regulation and function in V2a neurons, identifying key regulators specific to posterior identities.

The paper generates melanocytes from hPSCs through two distinct developmental trajectories and identifies T2-specific factors that promote melanoma metastasis.

This study uses caudalized human pluripotent stem cell organoids to model neural tube axial elongation, showing gene expression patterns and morphological features similar to development.