Hannah E. Young

Dynamic neuro-immune regulation of psychiatric risk loci in human neurons

The paper investigates how maternal and fetal immune activation interacts with genetic risk profiles to influence neuronal regulatory activity and psychiatric traits.

A computational genetic- and transcriptomics-based study nominates drug repurposing candidates for the treatment of chronic pain

This paper identifies drug repurposing candidates for chronic pain using genetics and transcriptomics, finding drugs with opposing gene expression effects to the disease.

Common genetic variation impacts molecular stress response in the brain

The paper identifies stress-interactive eQTLs that dysregulate gene expression in the brain under stress, uncovering novel genes linked to brain disorder risk in traumatic stress contexts.

Comparison of confound adjustment methods in the construction of gene co-expression networks

This study compares confound adjustment methods for gene co-expression network construction and finds that different methods significantly affect network architecture.

Expanding the Genetic Architecture of Nicotine Dependence and its Shared Genetics with Multiple Traits: Findings from the Nicotine Dependence GenOmics (iNDiGO) Consortium

The paper identifies novel genetic loci associated with nicotine dependence and shows genetic correlations with other smoking traits and comorbidities using genome-wide association studies.

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

This study identifies 206 new genomic loci and 1,041 genes associated with intelligence using a large GWAS meta-analysis of 279,930 individuals.