Substrate stress relaxation regulates monolayer fluidity and leader cell formation for collectively migrating epithelia.
Frank W. Charbonier, Junqin Zhu, Raleigh Slyman, Cole Allan, Ovijit Chaudhuri
This study shows that epithelial monolayers migrate faster on viscoelastic substrates with slower stress relaxation, due to increased fluidity and leader cell formation.
Proceedings of the National Academy of Sciences · Apr 9, 2025Peer-reviewedBiophysics