Author

Kseniia Dudnyk

The University of Texas Southwestern Medical CenterORCID 0000-0002-8161-3487Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jian ZhouiD· 2 shared Anastasia M. JackoiD· 1 shared Bruce NmeziiD· 1 shared Camilo ToroiD· 1 shared Chenlai ShiiD· 1 shared Donghong CaiiD· 1 shared Dongkyeong Kim· 1 shared Emanuel Loeza‐AlcoceriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetics

Jian ZhouORCID

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2 papers

Recent·Most cited

An oligodendrocyte silencer element underlies the pathogenic impact of lamin B1 structural variants

Bruce Nmezi, Guillermo Rodríguez Bey, Talia DeFrancesco Oranburg, Kseniia Dudnyk, Santana M. Lardo, Nathan Herdman, Anastasia M. Jacko, Sandy Rubio, Emanuel Loeza‐Alcocer, Julia Kofler, Dongkyeong Kim, Julia Rankin, Emma C. Kivuva, Nicholas J. Gutowski, Katherine R. Schon, , Quasar Saleem Padiath

The paper identifies a silencer element lost in ADLD patients that specifically targets oligodendrocyte overexpression of LMNB1, linking it to disease pathogenesis.

Nature Communications · Feb 5, 2025Peer-reviewedGenetics

Sequence basis of transcription initiation in human genome

Kseniia Dudnyk, Donghong Cai, Chenlai Shi, Jian Xu, Jian Zhou

This study identifies key sequence patterns that determine transcription initiation in human promoters using deep learning and experimental validation, showing conservation across mammalian species.

Science · Apr 25, 2024Peer-reviewedGenomics