Donghong Cai

This study shows that aging-related retrotransposon activation in stromal cells promotes Dnmt3a-mutant clonal hematopoiesis through inflammation.

The paper shows that LACTB2 in the liver regulates mitochondrial maturation to coordinate carbohydrate metabolism with brain development in mice.

The paper investigates the functional divergence of TBP homologs across species by analyzing their ability to complement TBP inactivation in yeast and identifies the role of the N-terminal domain in species-specific activity.

This study identifies key sequence patterns that determine transcription initiation in human promoters using deep learning and experimental validation, showing conservation across mammalian species.