Author

Ori Wald

Hadassah Medical CenterORCID 0000-0002-8189-0716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Abed KhalailehiD· 1 shared Agnes KlochendleriD· 1 shared Alexander M. AravanisiD· 1 shared Alon J. PikarskyiD· 1 shared Amit Korach· 1 shared Andrew M. James ShapiroiD· 1 shared Arash JamshidiiD· 1 shared Ayelet PeretziD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Abed KhalailehORCID

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2 papers

Recent·Most cited

A Novel Cisplatin-Based Prodrug Inhibits Lysine Deacetylases, Suppresses Nucleotide Excision Repair, and Overcomes Resistance

Ya’ara Negev-Korem, Esther Stern, Hadar Golan-Berman, Elisheva E. Heilbrun, Subhendu Karmakar, Yoram Soroka, Marina Frušić‐Zlotkin, Ofer Chen, Hiba Hassanain, Ori Wald, Dan Gibson, Ron Kohen, Sheera Adar

This study develops a novel cisplatin-based prodrug that inhibits lysine deacetylases and suppresses nucleotide excision repair, enhancing cisplatin's cytotoxicity and overcoming resistance.

bioRxiv · Oct 30, 2024 · PreprintMolecular Biology

A human DNA methylation atlas reveals principles of cell type-specific methylation and identifies thousands of cell type-specific regulatory elements

Netanel Loyfer, Judith Magenheim, Ayelet Peretz, Gordon M. Cann, Joerg Bredno, Agnes Klochendler, Ilana Fox-Fisher, Sapir Shabi-Porat, Merav Hecht, Tsuria Pelet, Joshua Moss, Zeina Drawshy, Hamed Amini, Patriss Wais Moradi, Sudharani Nagaraju, , Tommy Kaplan

The paper constructs a human DNA methylation atlas using whole-genome bisulfite sequencing of 39 cell types, revealing cell type-specific methylation patterns and regulatory elements.

Nature · Jan 4, 2023Peer-reviewedGenomics