Author

Radleigh G. Santos

Nova Southeastern UniversityORCID 0000-0002-8194-5502Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Clemencia PinillaiD· 2 shared Abbigayl E.C. BurtisiD· 1 shared Angel J. MagañaiD· 1 shared Austin E. GilleniD· 1 shared Beth A. Jirón TamburiniiD· 1 shared David J. OrlickyiD· 1 shared Destiny DeNicolaiD· 1 shared Haley M. Donow· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Clemencia PinillaORCID

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2 papers

Recent·Most cited

Antigen-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice.

Abbigayl E.C. Burtis, Destiny DeNicola, Megan E. Ferguson, Radleigh G. Santos, Clemencia Pinilla, Michael S. Kriss, David J. Orlicky, Beth A. Jirón Tamburini, Austin E. Gillen, Matthew A. Burchill

This study identifies antigen-driven CD8+ T cell clonal expansion in human and mouse MASH, showing their activation and functional differentiation in liver disease.

Hepatology · Jul 24, 2024Peer-reviewedImmunology

Structure-activity relationship of pyrrolidine pentamine derivatives as inhibitors of the aminoglycoside 6'-N-acetyltransferase type Ib

Jan Sklenicka, Tung Tran, María Soledad Ramirez, Haley M. Donow, Angel J. Magaña, Travis M. Lavoi, Yasir Mamun, Verónica Jiménez, Prem P. Chapagain, Radleigh G. Santos, Clemencia Pinilla, Marc A. Giulianotti, Marcelo E. Tolmasky

This study identifies pyrrolidine pentamine derivatives as inhibitors of AAC(6')-Ib, showing that structural modifications affect inhibitory activity and that molecular docking correlates with potency.

Antibiotics · Jul 19, 2024Peer-reviewedBiochemistry