Jessica A. Cardin

This paper introduces SSLD, a framework that learns shared neural-behavioral latent dynamics and private modality-specific variables, showing it accurately reconstructs signals and isolates behaviorally relevant information across multiple datasets.

The paper shows that visual experience enhances SST interneuron activity and suppresses VIP interneurons, leading to increased excitatory neuron selectivity and network synchrony.

This study investigates how noradrenergic signaling changes with behavioral states and its impact on cortical network activity and connectivity.

This study shows that visual fear conditioning leads to ACh release in visual cortex, enhancing neuronal responses and facilitating learned behavior.

The paper examines the developmental trajectory of somatostatin interneurons in the mouse visual cortex, showing their increasing influence on pyramidal neuron responses over time.

The paper identifies gamma events in mouse V1 cortex that predict visual detection and are modulated by task context.

This study investigates the mechanisms of reduced cortical cholinergic activity during focal seizures using an awake mouse model and electrophysiology, calcium imaging, and neurotransmitter sensing.

The paper uses a transformer model to analyze cholinergic and calcium signaling in mice during learning, finding spatiotemporal plasticity in frontal cortical subnetworks.

This study shows that traumatic brain injury disrupts functional connectivity in mice, with recovery and state-dependent changes in connectivity and theta power during stillness.

The paper introduces a long working distance air objective for multiphoton imaging in vivo, demonstrating its performance across multiple species and imaging systems.

The paper shows that higher-order thalamus sends state information to higher-order cortex, while corticocortical projections convey visual information.

This study investigates how VIP interneurons influence cortical circuit function and visual perception in mice by altering the selectivity of interneurons and pyramidal neurons for stimulus size.

This study introduces a framework to interpret neural frequency spectra by analyzing how temporal event distributions and waveform shapes influence spectral power, showing that power increases in specific bands do not always indicate oscillations.

This study shows that loss of ErbB4 in PV interneurons during embryonic development disrupts cortical circuit dynamics and neuronal connectivity.

The paper uses dual-color mesoscopic imaging in awake mice to show that cholinergic and cortical activity are spatiotemporally heterogeneous and linked to behavioral states.

The paper introduces new voltage sensors that enable simultaneous cellular-resolution activity imaging from multiple neuron-types in awake animals.

This study uses calcium imaging in awake mice to show that rapid changes in cortical functional connectivity encode spontaneous behaviors and reveal subnetworks not captured by traditional parcellation.

This paper describes a novel mouse model of focal limbic seizures that correlates behavioral impairment with cortical slow wave activity, similar to human temporal lobe seizures.

The paper investigates the role of three GABAergic interneuron populations in a mouse model of Rett Syndrome, finding distinct contributions to seizure, motor, and social behavior deficits.

The paper compares how different channelrhodopsin variants affect neural network activity in mice, finding distinct temporal patterns and effects on gamma-band activity.

The paper develops a method to simultaneously image local microcircuits and whole cortical activity in awake mice, and uses it to study neuron associations with network motifs.

This paper combines mesoscopic Ca2+ imaging and fMRI to study brain activity across spatiotemporal scales, finding correspondence between signals and stable connectivity matrices.