Kalpana Mandal

Embolization-on-a-chip: Novel Vascularized Liver Tumor Model for Evaluation of Cellular and Cytokine Response to Embolic Agents

This paper evaluates novel embolic agents using a vascularized liver tumor-on-a-chip model, finding that DESTH induces tumor cell death and alters cytokine levels and vascular morphology.

Metabolically intact nuclei are fluidized by the activity of the chromatin remodeling motor BRG1

This study shows that BRG1 activity fluidizes the nucleus, altering its stiffness and dissipating mechanical energy, with implications for nuclear mechanics and remodeling.

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

This study identifies the Piezo-Atr-Chek1-Cdc25 pathway as an inhibitory mechanism for axon regeneration, showing that disrupting it enhances regeneration in Drosophila and mammals.