Maneesha S. Inamdar

This study shows OCIAD2 upregulation during mesendoderm differentiation is TGFβ-dependent and essential for EMT, with implications for lineage commitment and tumor progression.

This paper presents a simplified, robust protocol for generating human gastruloids with high elongation efficiency and reproducibility across multiple stem cell lines.

This paper shows Rudhira regulates TGFβ signaling and microtubule stability during mouse vascular development through both direct and transcriptional mechanisms.

This study shows that reducing Asrij levels in an Alzheimer's disease mouse model decreases microglial inflammation and Aβ pathology, improving cognitive and neuronal outcomes.

This study shows mitochondrial activity regulates HSC fate and lineage choice during embryonic hematopoiesis in the AGM, with low mitochondrial activity promoting myeloid bias and high activity favoring lymphoid bias.

This study investigates the roles of ESCRT components in Drosophila blood progenitor maintenance, lineage choice, and immune response, revealing both autonomous and non-autonomous functions.

The paper identifies functional differences in JAK-STAT signaling between anterior and posterior progenitors in the Drosophila lymph gland, showing how compartmentalization affects immune response.

This study identifies Rudhira's role in cytoskeletal crosstalk during endothelial cell migration and angiogenesis, showing its necessity for microtubule-IF crosslinking and cell movement.