Author

Eglantine Hector

Centre National de la Recherche ScientifiqueORCID 0000-0002-8269-0652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Pierre J. MilpiediD· 2 shared Chuang DongiD· 1 shared Jad Sleiman· 1 shared Jean‐Marc Navarro· 1 shared Lama AwadaiD· 1 shared Laurent LimoziniD· 1 shared Martine Biarnes‐PelicotiD· 1 shared Philippe RobertiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

Pierre J. MilpiedORCID

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2 papers

Recent·Most cited

Antibody maturation in germinal centers selects mutants based on BCR-antigen bond mechanical resistance

Lama Awada, Jad Sleiman, Jean‐Marc Navarro, Rémy Torro, Martine Biarnes‐Pelicot, Eglantine Hector, Laurent Limozin, Chuang Dong, Pierre J. Milpied, Philippe Robert

The paper investigates antibody maturation in germinal centers, finding that mechanical resistance of BCR-antigen bonds, not affinity, drives selection during maturation.

bioRxiv · Mar 13, 2026 · PreprintImmunology

SeQuoIA: a single-cell BCR sequencing analysis pipeline for tracking selection mechanisms in germinal centres

Eglantine Hector, Pierre J. Milpied

SeQuoIA is a single-cell BCR sequencing pipeline that tracks selection mechanisms in germinal centres by inferring BCR-driven selection pressure from somatic mutation patterns.

bioRxiv · Feb 13, 2025 · PreprintImmunology