Michael Granato

This study identifies celsr3 and huntingtin as critical for long-range spinal cord regeneration in zebrafish, showing distinct roles in initiating and sustaining axonal growth.

This study identifies a glial-derived pathway involving Lh3 and Col18a1 that guides regenerating optic nerve axons toward the optic chiasm in zebrafish.

This study investigates the behavioral effects of isoform-specific NRXN1 deletions in zebrafish, showing unique and overlapping deficits in locomotion, sensorimotor behavior, and social behavior.

The paper identifies serotonin type-1 receptor signaling as a key regulator of early optic nerve regeneration in zebrafish, showing it promotes axonal regrowth but is dispensable during development.

This study shows that partial loss of DOT1L causes transcriptional, morphological, and behavioral defects in neurons across multiple models.

This paper identifies Celsr3's role in the development and connectivity of the zebrafish acoustic startle hindbrain circuit, showing its necessity for axon guidance and synaptic formation.

This study identifies a single base pair substitution in the syt7a gene in zebrafish linked to an acoustic startle threshold phenotype but shows it does not cause the observed behavioral changes.

This study investigates visual habituation in larval zebrafish using Ca2+ imaging and pharmacological screens, revealing complex, distributed neural mechanisms without a simple pharmacological relationship to behavior.

The paper shows that Schwann cells guide axon sorting at a nerve plexus during regeneration, restoring target-specific connectivity in zebrafish.

This study identifies cacna2d3 as a gene critical for habituation learning and startle sensitivity in zebrafish, with implications for human CNS disorders.

The paper identifies five molecular and circuit modules regulating habituation learning in zebrafish using pharmacogenetic and whole-brain activity analyses, revealing distinct roles for dopamine signaling.

This study shows that Agrin/Lrp4 signaling constrains MuSK activity in appendicular muscle synapse development, contrasting with its stimulatory role in axial muscle.

This study shows that hypomyelination in zebrafish larvae disrupts axonal conduction and behavior, linking myelination to neural circuit function.

This study identifies eight genes, including Dolk and Kv1.1, that regulate zebrafish startle behavior through a common genetic pathway, with Dolk affecting Kv1.1 protein localization.

The paper identifies Hip14 as a critical regulator of habituation learning in zebrafish by palmitoylating Kv1.1, affecting its subcellular localization and function.

The paper identifies Robo2 as a key regulator of target-selective peripheral nerve regeneration in response to glia-derived signals in zebrafish.

This study shows that visual habituation in larval zebrafish involves multiple independent processes that adapt different behavioural components, suggesting distributed plasticity rather than a single site of change.

The paper identifies a genetic basis for molecular asymmetry at vertebrate electrical synapses in zebrafish, showing that two Connexins function presynaptically and postsynaptically, respectively, and are required for escape responses.