Author

Zehra E.F. Demir

University of VirginiaORCID 0000-0002-8289-3118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

Matthew R. DeWittiD· 2 shared Natasha SheybaniiD· 2 shared Pouria TalebibarmiiD· 2 shared Thomas SherlockiD· 2 shared AeRyon KimiD· 1 shared Alexander L. KlibanoviD· 1 shared Andrew T ThedeiD· 1 shared Beyzanur G Ak· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Matthew R. DeWittORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cancer BiologyJournal for ImmunoTherapy of CancerPeer-reviewedAug 1, 2026

Focused Ultrasound Thermal Ablation and CD40 Agonism Reprograms Breast Tumor Immunity to Drive Regression and Memory

Zehra E.F. Demir, AeRyon Kim, Beyzanur G Ak…·Natasha Sheybani

This study shows that combining focused ultrasound thermal ablation with CD40 agonism enhances tumor immunity, leading to durable regression and immunological memory in breast cancer models.

DOI 10.1136/jitc-2026-015671

mouseexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintJun 11, 2026

Multimodal PET Defines a Goldilocks Thermal Window for Focused Ultrasound Ablation and Immunotherapy Combinations

Zehra E.F. Demir, Thomas Sherlock, Matthew R. DeWitt…·Natasha Sheybani

This paper identifies an optimal thermal dose for focused ultrasound ablation that balances tumor destruction with immunotherapy access using multimodal PET imaging.

DOI 10.64898/2026.06.10.731490

mouseimaging

𝕏 PostBluesky