Matthew R. DeWitt

This study shows that combining focused ultrasound thermal ablation with CD40 agonism enhances tumor immunity, leading to durable regression and immunological memory in breast cancer models.

This paper identifies an optimal thermal dose for focused ultrasound ablation that balances tumor destruction with immunotherapy access using multimodal PET imaging.

This study combines thermally ablative focused ultrasound with VEGFR2 blockade to enhance T cell-dependent anti-tumor immunity and synergize with checkpoint inhibition.

This paper develops a FUS-responsive granular hydrogel system that stabilizes through crosslinking and porosity control, showing potential for minimally invasive tissue regeneration.