Christopher Gerard Dowson

The paper identifies and optimizes bicyclic peptide inhibitors of Staphylococcus aureus α-hemolysin, achieving sub-micromolar affinity and demonstrating functional inhibition of toxin activity.

This study discovers and optimizes bicyclic peptide inhibitors of E. coli PBP3, showing high-affinity binding and broad-spectrum antimicrobial activity.

The paper introduces a VR software pipeline for visualizing protein-drug interactions and simulating molecular motions to improve drug design.