Dom Bellini

The paper presents structural studies of the archaeal CdvAB cell division machinery, showing CdvA forms helical filaments and CdvB adopts ESCRT-III-like folds, revealing membrane engagement mechanisms.

This study discovers and optimizes bicyclic peptide inhibitors of E. coli PBP3, showing high-affinity binding and broad-spectrum antimicrobial activity.

This study investigates the structural and functional changes in human sperm nuclear pore complexes (NPCs) during spermatogenesis, revealing a reduced central channel and altered transport dynamics.

This study shows CPF interacts with Pol II and promotes its dimerization, linking RNA 3'-end processing to transcription termination.

The paper uses in silico modeling to analyze the dynamics and flexibility of SARS-CoV-2 spike proteins and their mutations, finding that overall motion remains largely unchanged between wild-type and mutated structures.

The paper introduces a VR software pipeline for visualizing protein-drug interactions and simulating molecular motions to improve drug design.