Pietro Paolo Sanna

The paper identifies molecular alterations in the prefrontal cortex of individuals with alcohol use disorder and smoking, revealing distinct and combined pathway changes across cell types.

This study shows that N6-methyladenosine (m6A) RNA methylation regulates alcohol drinking and relapse by altering gene expression in the hippocampus of mice.

This study shows that S1P receptor agonists reduce alcohol drinking in rodent models and identify S1P signaling as a potential therapeutic target for alcohol use disorder.

This study shows that functional recovery from dopamine neuron grafts depends on neurite outgrowth, not graft size or neuron content, and identifies gene expression patterns linked to graft efficacy.

The paper uses GSEA to analyze gene expression patterns in HIV-infected patients with and without neurocognitive impairments, finding that neuroinflammation and white matter dysfunction precede NCI.