Author

Riccardo Maccioni

Scripps Research InstituteORCID 0000-0003-1349-4903Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Irene LorraiiD· 3 shared Itzamar Torres· 3 shared Pietro Paolo SannaiD· 3 shared Roberta PuligaiD· 3 shared Vez Repunte‐CanonigoiD· 3 shared Jorge Marquez Gaytan· 2 shared André FisahniD· 1 shared Annika Wagener· 1 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Irene LorraiORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 16, 2025

N6-methyladenosine RNA methylation is a novel epitranscriptomic regulator of excessive alcohol drinking and vulnerability to relapse

Riccardo Maccioni, Irene Lorrai, Itzamar Torres…·Pietro Paolo Sanna

This study shows that N6-methyladenosine (m6A) RNA methylation regulates alcohol drinking and relapse by altering gene expression in the hippocampus of mice.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 15, 2025

Gene network inference and master regulator analysis identifies the estrogen-related receptor gamma (ERRγ) as a therapeutic target for alcohol use disorder (AUD).

Irene Lorrai, Riccardo Maccioni, Itzamar Torres…·Pietro Paolo Sanna

DOI 10.1101/2025.11.15.688629

humanmouse

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 15, 2025

Sphingosine-1-phosphate (S1P) signaling as a novel therapeutic target for alcohol abuse.

Irene Lorrai, Riccardo Maccioni, Chenhao Wu…·Pietro Paolo Sanna

This study shows that S1P receptor agonists reduce alcohol drinking in rodent models and identify S1P signaling as a potential therapeutic target for alcohol use disorder.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 24, 2022

Signal Peptide Peptidase-Like 2b affects APP cleavage and exhibits a biphasic Aβ-mediated expression in Alzheimer's disease.

Riccardo Maccioni, Caterina Travisan, Stefania Zerial…·Simone Tambaro

This study shows that SPPL2b affects APP cleavage and has biphasic Aβ-mediated expression in Alzheimer's disease, suggesting it as a potential drug target.

1 citation

humanmouse

𝕏 PostBluesky