Synthetic BiologybioRxivPreprint
Backbone extension acyl rearrangements enable cellular synthesis of proteins with internal β2-peptide linkages
Leah Tang Roe, Carly K. Schissel, Taylor L. Dover…·Alanna Schepartz
This paper introduces a method to synthesize proteins with internal β2-peptide linkages in cells by using a post-translational rearrangement after incorporating specific -hydroxy acid monomers.
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