Carly K. Schissel

This paper develops a high-throughput platform to discover arginine-depleted cell-penetrating peptides for improved antisense delivery in Duchenne muscular dystrophy, showing reduced toxicity and enhanced efficacy.

The paper introduces a new assay called PARTI to measure monomer-specific acyl-tRNA levels in cells and applies it to study non-amino acid monomer incorporation into proteins.

This paper introduces a method to synthesize proteins with internal β2-peptide linkages in cells by using a post-translational rearrangement after incorporating specific -hydroxy acid monomers.

Deep learning generates de novo large functional abiotic polymers that deliver antisense oligonucleotides to the nucleus.