Author

Yongrui Zhang

University of SouthamptonORCID 0000-0002-8331-7315Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aarya Vaikakkara ChithraniD· 1 shared Amber S. CooperiD· 1 shared Amritpal K. MudheriD· 1 shared Ben BatcheloriD· 1 shared Benjamin BoehmeiD· 1 shared Bradley RichardsoniD· 1 shared Douglas W. AllaniD· 1 shared Efthimios M. C. SkoulakisiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aarya Vaikakkara ChithranORCID

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1 paper

Recent·Most cited

Aggregation promoting sequences rather than phosphorylation are essential for Tau-mediated toxicity in Drosophila

Amber S. Cooper, Bradley Richardson, Eva Ruiz, Yongrui Zhang, Ben Batchelor, Aarya Vaikakkara Chithran, Jie Liu, Tianshun Lian, Miguel Ramírez Moreno, Benjamin Boehme, Seyedehleila Abtahi, George Devitt, Lovesha Sivanantharajah, Efthimios M. C. Skoulakis, Douglas W. Allan, Amritpal K. Mudher

This study shows that Tau aggregation, not phosphorylation, is critical for neurotoxicity in Drosophila, suggesting that targeting aggregation may be more effective than targeting phosphorylation in tauopathies.

bioRxiv · Dec 22, 2024 · PreprintNeuroscience