GeneticsbioRxivPreprint
Efficient repair of human homozygous genetic mutation by CRISPR/Cas9 mediated interlocus gene conversion
Fei Yang, Jingtao Pang, Guolong Liu…·Yuxuan Wu
This study demonstrates that CRISPR/Cas9-mediated gene conversion can efficiently repair genetic mutations in hematopoietic stem cells without requiring exogenous DNA templates.
DOI 10.1101/2022.09.05.506576