Author

Joanna Demilly

Commissariat à l'Énergie Atomique et aux Énergies AlternativesORCID 0000-0002-8345-9567Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:non-human primate· 1

Frequent Co-Authors

Alix Lebreton· 1 shared Allwyn PereiraiD· 1 shared Anne Marie DouariD· 1 shared Anthony Mellet· 1 shared Antoine ChaffioliD· 1 shared Bérangère Robert· 1 shared Caroline Le GuineriD· 1 shared Celia Couzinié· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alix Lebreton

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2 papers

Recent·Most cited

Intracellular accumulation of AAV6 genomes governs microglia reactivity and the inflammatory response in retinal gene therapy

Allwyn Pereira, Jean-Baptiste Ducloyer, Joanna Demilly, Estelle Toublanc, Lyse Libeau, Bérangère Robert, Anthony Mellet, David Augereau, Léa Comtesse, Thibaut Larcher, Alix Lebreton, Paul Socheleau, Marion G�rard, Malo Journou, Celia Couzinié, , Thérèse Cronin

This study shows that intracellular accumulation of AAV6 genomes in microglia drives reactivity and inflammation in retinal gene therapy.

bioRxiv · Oct 11, 2026 · PreprintNeuroscience

Optogenetic therapy: High spatiotemporal resolution and pattern recognition compatible with vision restoration in non-human primates

Grégory Gauvain, Himanshu Akolkar, Antoine Chaffiol, Fabrice Arcizet, Mina A. Khoei, Mélissa Desrosiers, Céline Jaillard, Romain Caplette, Olivier Marre, Stéphane Bertin, Claire-Maëlle Fovet, Joanna Demilly, Valérie Forster, Elena Brazhnikova, Philippe Hantraye, , Serge A. Picaud

The paper evaluates an optogenetic construct for vision restoration in non-human primates, demonstrating high temporal resolution and visual acuity above legal blindness.

Communications Biology · Jan 27, 2021Peer-reviewedNeuroscience