Failed remyelination of the non-human primate optic nerve leads to axon degeneration, retinal damages and visual dysfunction.
Nadège Sarrazin, Estelle Chavret-Reculon, Corinne Bachelin…·Anne Baron‐Van Evercooren
This paper presents a non-human primate model of optic nerve demyelination that recapitulates key features of MS lesions, showing failed remyelination, axonal degeneration, and visual dysfunction.