Ectopic expression of two cone opsins in mouse RGCs results in opposite responses to light stimulation, likely due to differential G protein activation
Marco Rucli, Nika Vrabic, Corentin Joffrois…·Deniz Dalkara
This study shows that expressing short-wavelength cone opsin in RGCs causes hyperpolarization, opposite to mid-wavelength opsin's depolarization, due to different G-protein activation.