Ivan Košík

This study shows that SARS-CoV-2 syncytia reduce interferon and antibody effectiveness, explaining the evolution of fusogenic viral variants.

CountASAP converts ASAPseq FASTQ data into count matrices for downstream analysis.

This study investigates how vaccine antigen valency and pre-existing memory B cells influence B cell responses to drifted influenza virus, showing differential effects on germinal center dynamics and immunodominance.

This paper uses advanced microscopy to show that SARS-CoV-2 attaches to and enters cells via heparan sulfate clusters, not ACE2, and that blocking HS binding inhibits viral infection.

This study identifies antibody avidity as a correlate for in vivo efficacy of broadly reactive anti-alphavirus antibodies and links it to Fc-dependent mechanisms.

This study compares the early single-cell transcriptional responses to live attenuated and inactivated Yellow Fever vaccines in mice, identifying distinct kinetic patterns and differential gene expression.

The paper forecasts human influenza A virus hemagglutinin evolution by identifying a glycan clock pattern, predicting glycan additions and pandemic potential.