Raphaël Pantier

This study identifies a novel N-terminal region in TET1 that binds nucleosomes, enabling chromatin association in mouse embryonic stem cells through structural and biochemical validation.

This study shows SALL4 binds across the genome to shape chromatin and gene expression in stem cells.

This study shows that TET protein deficiency in mouse ESCs leads to impaired somatic differentiation and accelerated germline entry.

This study identifies tetramerisation as essential for SALL transcription factor function, showing its role in DNA binding and linking it to developmental disorders.

The paper identifies SALL4 as a protein that interprets DNA base composition by binding to AT-rich motifs, and shows its role in controlling cell fate through regulation of AT-rich gene expression.