Elisa Barbieri

This study shows OTX2 controls chromatin accessibility to promote somatic differentiation over germline fate in embryonic cells.

This study identifies a direct interaction between NANOG and RNA Polymerase II that regulates transcription and ESC self-renewal.

This study shows that TET protein deficiency in mouse ESCs leads to impaired somatic differentiation and accelerated germline entry.

The paper identifies a PP2A-Integrator complex that opposes CDK9 activity to regulate transcription and shows its therapeutic synergy in leukemia.

The paper introduces fastGRO, a method for rapid and scalable profiling of nascent RNA, showing it is more comprehensive and scalable than existing techniques.